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Splanchnic inversion (kusanganisira yakazara splanchnic inversion [dextrocardia] uye chikamu splanchnic inversion [levocardia]) isingawanzo kuberekwa kwekukura kwekusagadzikana umo kutungamira kwekugoverwa kwe splanchnic muvarwere kunopesana neavanhuwo zvavo. Takaona kuwedzera kukuru kwehuwandu hwe fetal visceral inversion kesi dzakasimbiswa neultrasound muchipatara chedu mwedzi mishoma mushure mekudzimwa kwe "zero clearance" mutemo weCCIDID-19 muChina.

Nokuongorora ruzivo rwekliniki kubva kumakamuri maviri ekudzivirira munzvimbo dzakasiyana-siyana dzeChina, takasarudza chiitiko che fetal visceral inversion kubva munaJanuary 2014 kusvika munaJuly 2023. Mumwedzi minomwe yekutanga ye2023, chiitiko chemukati inversion (nguva dzose prenatal ultrasonography uye kuongororwa panguva inenge 20 kusvika ku24 zera rekuongorora) protocol kana 24 vhiki yekudzidzira kunze kwechidzidzo che gesta. nguva dzakakwirira kudarika avhareji yegore negore chiitiko che 2014-2022 munzvimbo mbiri (Mufananidzo 1).

Chiitiko che visceral inversion chakakwira muna Kubvumbi 2023 uye chakaramba chakakwirira kusvika munaJune 2023. Kubva munaJanuary 2023 kusvika munaJuly 2023, 56 zviitiko zve splanchnosis zvakawanikwa (52 yakazara splanchnosis uye 4 chikamu splanchnosis). Huwandu hwehutachiona hweSARS-CoV-2 hwakawedzera mushure mekudzimwa kweiyo COVID-19 "zero clearance" mutemo, ichiteverwa nekuwedzera kwenyaya dze visceral inversion. Zvinofungidzirwa kuti kuvhiya kwehutachiona hweSARS-CoV-2 kwakatanga kutanga kwaZvita 2022, kwakakwira kusvika Zvita 20, 2022, uye kwakapera mukutanga kwaFebruary 2023, kuchizokanganisa 82% yehuwandu hweChina. Kunyange pasina mhedziso inogona kutorwa nezve causality, zvatinoona zvinoratidza mubatanidzwa unobvira pakati peSARS-CoV-2 kutapukirwa uye fetal visceral inversion, izvo zvinokurudzira kuenderera mberi.kudzidza.

Mufananidzo A unoratidza chiitiko chakasimbiswa che fetal splanchnic inversion munzvimbo mbiri dzekuzvara kubva muna Ndira 2014 kusvika muna Chikunguru 2023. Nhamba dziri pamusoro pebharichati dzinoratidza huwandu hwenyaya dzegore rega rega. Chiitiko chakashumwa sehuwandu hwezviitiko pavakadzi 10,000 vane pamuviri vakaongororwa ultrasound. Mufananidzo B unoratidza huwandu hwezviitiko zvakasimbiswa zve visceral inversion kubva muna Ndira 2023 kusvika Chikunguru 2023 paChina Welfare Society International Peace Maternal and Child Health Hospital (IPMCH) muShanghai neHunan Provincial Maternal and Child Health Hospital (HPM) kuChangsha.

Congenital visceral inversion inosanganiswa neabnormal morphogenetic hormone kugovera uye kuruboshwe-kurudyi murongi cilium kusagadzikana mukutanga gestation nhanho ye embryo kuruboshwe-kurudyi axis asymmetry. Kunyangwe kutapurirana kwakamira kweSARS-CoV-2 kuchiri kukakavara, kutapukira kwe embryo mukuzvitakura kwekutanga kunogona kukanganisa fetal visceral asymmetrical kukura. Uye zvakare, SARS-CoV-2 inogona kukanganisa zvisina kunanga kuruboshwe-kurudyi matishu centre basa kuburikidza nekupindirana kwayo kwekuzvimba mhinduro yaamai, nekudaro ichikanganisa visceral asymmetrical kukura. Muzvidzidzo zvenguva yemberi, kumwe kuongorora kunodiwa kusimbisa kuti genetic abnormalities inoenderana neprimary ciliary dyskinesia iyo inogona kunge isina kuwanikwa muprenatal genetic screening haisi mhosva yezviitiko izvi, uye kuongorora zvinogona kuita zvezvakatipoteredza mukuwedzera kwe visceral inpositions. Izvo zvinofanirwa kucherechedzwa kuti kunyangwe chiitiko che visceral inversion chakawedzera munzvimbo mbiri dzekuzvara mushure mekuvhiya kweSARS-CoV-2 hutachiona, chiitiko chekiriniki che visceral inversion chichiri kushoma.